VISTA™ Carrier Screening for Couples
An innovative genetic test that helps assess the risk of inherited conditions before pregnancy. The test determines whether prospective parents are carriers of genetic disorders and provides a basis for informed and responsible family planning.
A healthy start for your baby begins with responsible genetic planning
Even if both parents are completely healthy, they may still be carriers of inherited disorders. Most genetic conditions are passed on silently – without any prior symptoms or family history. VISTA™ Carrier Screening allows you to assess this risk before pregnancy and helps prospective parents make informed decisions to support the child’s health and peace of mind throughout the family-planning journey.
How does VISTA™ Carrier Screening help assess the risk of inherited disorders?
„VISTA™ Carrier Screening“ analizuoja genus, susijusius su daugiau nei 1200 paveldimų ligų, įskaitant:The test determines whether prospective parents are carriers of inherited genetic conditions – even if there is no known history of such conditions in their families. Genetic disorders may be inherited in an autosomal recessive, autosomal dominant, or sex-linked manner, and the likelihood depends on the genes carried by both partners.
VISTA™ Carrier Screening analyses genes associated with more than 1,200 inherited conditions, including:
Cystic fibrosis, sickle cell anaemia, albinism, phenylketonuria (autosomal recessive disorders)
Duchenne muscular dystrophy, haemophilia B (X-linked disorders)
Genetic reassurance for family planning
VISTA™ Carrier Screening gives you the opportunity to find out – before conception – whether prospective parents are carriers of inherited disorders. This not only reduces uncertainty and anxiety, but also enables responsible family planning based on scientific evidence.
Find out which conditions you could pass on to your child
The test identifies whether both partners carry the same gene mutation that could cause an inherited condition in a baby – in which case the risk can be as high as 25%.
Three testing packages to match your needs
You can choose from three test panels – from 11 to more than 1,200 inherited conditions – depending on your individual risk level and family history.
Informed decisions about next steps
Test results help you consider options such as genetic counselling, PGD/IVF possibilities, or other solutions that can help prevent the transmission of inherited disorders.
Reducing the societal burden of genetic disease
Screening programmes help reduce the prevalence of inherited disorders in the population, as already demonstrated for β-thalassaemia and Tay–Sachs disease in Europe and the United States.
When and for whom is the test recommended?
For those planning to start or expand their family
The test enables early assessment of genetic risk and supports informed decisions before conception.
For those expecting a baby
Even if the pregnancy has already begun, the test helps evaluate the potential risk of passing inherited conditions to the child.
For couples with no known family history of inherited disorders
Even completely healthy parents can be carriers of recessive conditions – the test reveals these “hidden” risks.
For those with inherited disorders in the family
If genetic conditions have occurred in your family, the test helps you better understand inheritance likelihood and potential risks.
VISTA™ reliability: accuracy and quality metrics
The test uses reliable laboratory technologies to accurately assess the risks of autosomal recessive and sex-linked inherited disorders. VISTA™ Carrier Screening demonstrates high sensitivity, specificity, and reliability in detecting mutations in the targeted regions.
3 advanced test options: 11, 172, and 1200+ genetic conditions
Next-generation sequencing
Genetically informed family planning
Take the VISTA™ Carrier Screening test and find out whether your child could inherit a genetic condition.
For Specialists
All key information in one place – from the genes analysed to test accuracy and clinical value. This section is intended for specialists who want a detailed understanding of the test rationale, structure, and practical applications.
VISTA™ Carrier Screening is a genetic carrier screening test for recessive monogenic disorders, intended for couples planning a pregnancy or in early pregnancy. This is particularly relevant for couples concerned about their baby’s health, as answers are often only obtained after the 10th week of pregnancy or after the child is born.
Autosomal recessive disorders affect 1.7 to 5 babies per 1,000, while autosomal dominant disorders affect about 1.4 per 1,000. These figures highlight that even without a clear family history, parents may still be carriers of genetic conditions.
The prevalence of genetic disorders varies significantly across populations. For example, Tay–Sachs disease occurs 100 times more frequently in the Ashkenazi Jewish population than in the general population – 1 in 3,200 versus 1 in 320,000 cases, respectively.
Scientific studies show that systematic carrier screening substantially reduces the prevalence of certain disorders: cases of β-thalassaemia in Greece and Italy decreased by 80–90%, and Tay–Sachs decreased by 90% in the United States and Israel. This significantly reduces the burden on the healthcare system.
VISTA™ Carrier Screening offers three panel options for autosomal recessive and X-linked disorders:
– Mini Panel – analyses 13 genes (>5,400 variants) associated with 11 disorders.
– Targeted Panel – analyses 164 genes (>10,000 variants) associated with 172 disorders.
– 1200+ Panel – one of the broadest inherited disease panels worldwide, analysing >1,200 genes associated with >1,200 disorders.
The test uses peripheral blood from the prospective parents. Analysis is performed using target enrichment and next-generation sequencing (NGS). Results are provided within 4–6 weeks from receipt of the sample.
